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| Lectranal® and intradermal inflammatory reactions |
| The objective of this research was to confirm the previously conducted research on the effect of Lectranal® in the menagement of inflammatory reactions using intradermal testing. |
METHODS
Freund’s adjuvant was intradermally injected into a group of mice. After 4 days of treatment with Lectranal®, the inflammatory process was visualized by methylene blue dye and after that the size of the oedema was measured.
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 Figure 1. Reaction in mice that were given Lectranal®
In mice that were given Lectranal®, no significant development of oedema occurred.
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 Figure 2.Inflammatory reaction without the Lectranal® administration |
The size of the oedema without the Lectranal® treatment was up to 4 times greater.
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CONCLUSION
Lectranal® attenuates the inflammatory reaction induced by Freund’s adjuvant and prevents the occurrence of oedema, which confirms the results of the former research on Lectranal®’s anti-inflammatory effect.
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AUTHORS
Hadžija M., Popović Hadžija M., Korolija M.
Ruđer Bošković Institute, Zagreb 2006
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