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According to animal gene studies it is possible to assume that Lectranal® aims specifically at the imbalance of the immune system that triggers the overproduction of substances that cause allergy symptoms.
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| A change in relb gene activity is noted in Th1 cells. This could affect numerous reactions, which via IFN-gamma: |
- shift the Th1/Th2 balance in favour of Th1: by recruiting them from Th0 and by the enhanced multiplication of Th1
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- cause the proliferation of specific B-clone lymphocytes into plasma cells that produce IgG
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Ikbkg gene activity and translocation of the NF-kB transcription factor is noted inB lymphocytes, which suggest:
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- the formation of the clonal selection of specific B lymphocytes and the formation of memory cells, which then transform into plasma cells and produce IgG
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The produced IgGs could enable the macrophages to opsonize and phagocytize the allergen, and to neutralize it without the appearance of a symptomatic reaction.
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