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Research

EFFICACY AND SAFETY OF LECTRANAL® IN THE TREATMENT OF SEASONAL ALLERGIC RHINITIS SYMPTOMS
In order to determine efficacy and safety of Lectranal® in the treatment of seasonal allergic rhinitis symptoms, a randomized, double-blind, placebo controlled clinical study was conducted in Dubrava University Hospital in Zagreb.
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Preclinical toxicity study on Lectranal®
To determine the safety profile of allergy-relieving ingredient Lectranal®, a multiple-dose, 28-day toxicity study was performed on mice. The study was perfomed at the Ruđer Bošković Institute in Zagreb according to OECD protocol 407. Since Lectranal® requires an enteric delivery, in this...
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Lectranal® and intradermal inflammatory reactions
The objective of this research was to confirm the previously conducted research on the effect of Lectranal® in the menagement of inflammatory reactions using intradermal testing.
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An assay for immunoglobulines in the blood of mice treated with Lectranal®
The objective of this research was to determine how the Lectranal® used to treat inflammatory processes affects the level of protective immunoglobulines in the blood.
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Lectranal®, inflammatory reaction, and gene expression in mouse spleen
The objective was to assess the genetic base of the anti-inflammatory effect of Lectranal® using the gene chip method on mouse spleen cells.
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The effect of Lectranal® on the immunoregulation of inflammatory processes in mice
The objective of this research was to ascertain the effect of Lectranal® on the immunoregulation of inflammatory processes by verifying its function and the expression of the ikbkg, relb, and cd3e genes using Real Time PCR (RT-PCR) technology.
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